Thus, the DNA methylation is imposed on the transition between the active versus repressed transcription state for CD133 only in tumors. 这样,DNA甲基化发生于肿瘤中CD133的活化状态到抑制转录的过渡中。
However, this is also a fundamental step in the transition of tumors from a dormant state to a malignant state, an excessive and deregulated angiogenic response is thought to contribute to cancer, and other diseases. 同时也是肿瘤组织从良性转化为恶性过程中的基本步骤,过多的、非常规的血管新生反应被认为和癌症等疾病有关。
Therefore, designing a ferrofluid sample with low cluster disruption transition temperature could be a possible way to improve heating efficiency, and meanwhile choose a proper frequency to make the clusters disrupt at a low temperature and let them work in the monomer state to heat the tumors. 因此可通过设计具有较低聚集体分离相变温度的磁流体来提高热疗效率,并选择合适的频率,使聚集体在较低温度时就能完全分离成单体,从而工作在单体状态下继续加热。